Table 1.
Prevalence of erm(B) and mef(A) genes among azithromycin-resistant Streptococcus pneumoniae isolates from 22 hospitals in Taiwan from 2006 to 2010
| Resistant gene | No. (%) of isolates, by study period | Total (n = 486) | ||||
|---|---|---|---|---|---|---|
| 2006 | 2007 | 2008 | 2009 | 2010 | ||
| (n = 110) | (n = 110) | (n = 153) | (n = 53) | (n = 60) | ||
| erm(B)-positive | 66 (60) | 65 (59) | 92 (60) | 24 (45) | 42 (70) | 289 (59) |
| mef(A)-positive | 33 (30) | 26 (24) | 33 (22) | 11 (21) | 3 (5) | 106 (22) |
| mef(A)/erm(B)-positive | 11 (10) | 19 (17) | 28 (18) | 18 (34) | 15 (25) | 91 (19) |
| P-value* | - | 0.1683 | 0.8716 | 0.0224 | 0.3091 | |
*P-value for temporal change of mef(A)/erm(B)-positive by study period.