Table 2.

Clinicopathological factors associated with disease-free survival and overall survival in patients with breast cancer.

Variable	Disease-free survival				Overall survival
	Univariate analysis	Multivariate analysis			Univariate analysis	Multivariate analysis
	P-value	Hazard ratio	95% CI	P-value	P-value	Hazard ratio	95% CI	P-value
Age	0.76	0.93	0.29–2.24	0.71	0.62	1.21	0.31–2.36	0.66
Menopausal status	0.35	1.11	0.26–3.12	0.38	0.29	1.38	0.47–3.11	0.32
TNM stage	0.07	2.38	0.92–6.77	0.06	0.04	3.31	1.38–7.29	0.02
Grade	0.01	3.19	2.13–10.02	0.003	0.08	2.39	0.87–6.32	0.09
Histological type	0.12	0.79	0.23–3.19	0.24	0.33	1.28	0.38–3.03	0.67
Lymphonodus status	0.03	4.12	1.98–15.21	0.007	0.009	2.98	1.86–10.02	0.012
ER status	0.34	1.67	0.57–2.78	0.18	0.19	1.39	0.38–2.93	0.31
PR status	0.38	1.93	0.78–3.19	0.21	0.27	1.71	0.27–3.12	0.29
HER2 status	0.41	1.98	0.68–2.99	0.19	0.32	1.38	0.82–3.58	0.11
Serum soluble E-cad level	0.01	3.38	2.47–11.89	0.009	0.03	2.97	1.28–9.11	0.017