Table 2.

Effects of Pressure Elevation, Finasteride, Dutasteride, and the NMDAR Antagonist (APV) on the Density of Damaged GCs in the Middle Retina

Condition (n)	GC ± SD (P)
10 mm Hg (5)	0.6 ± 0.4 (–)
75 mm Hg (7)	8.8 ± 3.6 (0.0005)*
75 mm Hg + 1 μM Fin (5)	38.7 ± 6.1 (<0.0001)*
75 mm Hg + 1 μM Fin + 100 μM APV (5)	2.3 ± 1.2 (0.0169)†
75 mm Hg + 1 μM Duta (5)	33.2 ± 4.0 (<0.0001)*
75 mm Hg + 1 μM Duta + 100 μM APV (5)	2.5 ± 1.6 (0.0328)†

Data are the mean ± SD. The density of damaged GCs was counted per 500 μm of retina. P values were calculated versus control (10 mm Hg) by Student's t-test. P values are calculated by Student's t-test compared to 10 mm Hg. Duta, dutasteride.

^* P < 0.001.

^† P < 0.05.