Skip to main content
. Author manuscript; available in PMC: 2014 Dec 30.
Published in final edited form as: J Thromb Haemost. 2012 Aug;10(8):1631–1645. doi: 10.1111/j.1538-7836.2012.04814.x

Table 1. Platelet count, volume and surface glycoprotein expression in control and deficient platelets.

Control fyn−/−lyn−/− fgr−/−lyn−/− Chimeric control fyn−/−src−/− lyn−/−src−/−
PC, 103 mm−3 366 ± 42 823 ± 47 267 ± 49** 744 ± 52 813 ± 32 481 ± 49**
MPV, μm3 5.5 ± 0.1 6.2 ± 0.2** 6.3 ± 0.2** 5.4 ± 0.1 5.2 ± 0.1 5.7 ± 0.1
GPIb 50.4 ± 1.0 50.8 ± 4.9 37.9 ± 3.5* 41.2 ± 2.5 44.5 ± 3.3 36.2 ± 1.9*
GPIIb 89.5 ± 12.8 108.9 ± 15.6 104 ± 23 103.5 ± 17.0 118.3 ± 12.3 89.6 ± 7.9
GPVI 16.7 ± 1.0 22.2 ± 1.6 15.9 ± 0.5 19.9 ± 2.4 18.5 ± 2.5 16.7 ± 0.4
α2 3.6 ± 0.5 3.3 ± 0.4 3.7 ± 1.0 3.4 ± 0.3 3.6 ± 0.1 3.1 ± 0.4

Whole blood platelet count and mean platelet volume (MPV) for control and deficient mice platelets were analyzed with an automated blood analyzer (ABX Pentra 60). Results are expressed as means ± standard error of the mean (SEM) for at least six mice per group. Expression of glycoproteins on the platelet surface was determined by flow cytometry using specific fluorescein isothiocyanate-labeled antibodies. Results are expressed as median fluorescence intensity ± SEM for at least four mice per group. One-way anova.

*

P < 0.05,

**

P < 0.01 vs. respective control.