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. 2014 Dec 30;9(12):e115875. doi: 10.1371/journal.pone.0115875

Table 1. Symbols and abbreviations used in this paper.

MWB Mean Worm Burden
SWB Stratified worm burden
NB Negative binomial (distribution)
MDA Mass drug administration
FOI Force of infection
Inline graphicBRN or Basic reproduction number in MacDonald MWB system
Inline graphic critical BRN-type parameter for breakpoint in MWB system
H Total host population
Inline graphic n-th human strata in SWB system (population fraction carrying n worms)
Inline graphic Demographic sources for nth strata Inline graphic in SWB system
Inline graphic Worm increment in SWB formulation
w Worm burden (MWB), Inline graphic−1st moment of SWB system
u Inline graphic2nd moment of SWB system:
W Total worm population ( = H w)
U Total 2nd moment ( = H u)
Inline graphic Source terms in the w- and u- equations
k NB (negative binomial) aggregation parameter
Inline graphic Human population turnover rate (.02−.05/year)
Inline graphic Worm mortality rate ( = 1/4 years)
Inline graphic Snail mortality ( = 5/year)
Inline graphic Human FOI ( = mean rate of adult worm accumulation in human hosts)
Inline graphic Snail FOI (transition rate “susceptible” −> “infected”)
Inline graphic Mated female number for mixed strata (i males and j females)
Inline graphic Mated female count for n-th strata made of n adult worms
Inline graphic Total mated female count in host population
Inline graphic Mating function in MacDonald (MWB) system with NB worm distribution
Inline graphic Allee mating hurdle factor (Inline graphic)
A Transmission rates (snail->human) per single infected snail
B Transmission rates (human->snail) per mated female
Inline graphic Relative transmission rates
Inline graphic Infectious prevalence in MWB system with mean w, and NB aggregation k
Inline graphic Inline graphicInfectious prevalence in SWB system with FOI Inline graphic, and host turnover
Inline graphic Reduced “snail equilibrium” function for MWB (MacDonald) system
Inline graphic Reduced “snail equilibrium” function for SWB system
Inline graphic Drug efficacy (fraction of worms surviving a single dose)
f Population fraction cover in MDA
E Mean egg count in host population
Inline graphic Egg production/mated female
Inline graphic Equilibrium levels for MWB, SWB systems