Figure 3. (A and B). Effects of inhibitors of intracellular signaling pathways on P2Y₆R-mediated glucose uptake.

C2C12 cells (A) or 3T3-L1 cells (B) were preincubated with inhibitors of MAPK (U0126, 10 µM) and AMPK (Compound C, 10 µM) followed by treatment with P2Y₆R agonist MRS2957. * P<0.05, when compared to controls, ^# P<0.05, when compared to MRS2957, 100 nM (n = 3).