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. 2014 Dec 30;9(12):e116268. doi: 10.1371/journal.pone.0116268

Table 1. Demographic, microbiologic and Mtb exposure characteristics of study participants.

Cases (n = 23) TST+ (n = 64) TSTC (n = 26) PTST (n = 39) p–value
Age, median (range) 31 (27–35) 29 (20–38) 29 (23–49) 28 (20–45) ns
Male gender, n (%) 16 (70) 32 (50) 13 (50) 16 (41) ns
Presence of a BCG scar, n (%) 9/20 (45) 35/63 (56) 16/26 (62) 19/39 (49) ns
Baseline TST size, median (min., max, IQR) 0 (0,16,0) 14 (10,28,9) 0 (0,5,0) 0 (0,5,0) p<0.001
6 month TST size, median (min., max; IQR) na na 18 (10,25,6) 0 (0,5,0) p<0.001
Sleeping Proximity to Index Case
Same bedroom, n (%) 17 (27) 3 (11) 3 (8)
Different bedroom, n (%) 29 (45) 15 (58) 16 (41)
Different house, n (%) 18 (28) 8 (31) 20 (51) p = 0.041*
Smear Grade of Index Case
Grade 1, n (%) 2 (9) 9 (14) 1 (4) 8 (21)
Grade 2, n (%) 9 (39) 27 (42) 12 (46) 15 (38)
Grade 3, n (%) 12 (52) 28 (44) 13 (50) 16 (41) ns
Spoligotype of Index Case where known n = 21 n = 58 n = 24 n = 34
M. tuberculosis, n (%) 11 (52) 35 (60) 19 (79) 27 (79)
M. africanum, n (%) 10 (48) 23 (40) 5 (21) 7 (21) ns
Days to Positivity of Index Case Cultures
Days, median (IQR) 9 (17) 12 (17) 6.5 (10) 6 (18) ns

* Fisher's exact test: p = 0.017 for proximity between TST+ and PTST. ns = not significant; TST+ = TST positive; TSTC = TST converters; PTST = persistently TST negative; na = not assessed; IQR = interquartile range.