Table 3. Results of univariate logistic regression for the development of cervical lymph node metastasis in OSCC.
| Variable | Pathologic nodal classification | Univariate logistic regression | |||||||
| Negative (n = 42) | Positive (n = 46) | Odds ratio | 95% confidence interval | p value | Overall test | ||||
| Age | (years) | 66.9±11.6 | 62.5±11.4 | 0.97 | 0.93 | - | 1.00 | 0.078 | 0.078 |
| Sex | Women | 16 | 16 | 1.00 | 0.747 | ||||
| Men | 26 | 30 | 1.15 | 0.48 | - | 2.75 | 0.747 | ||
| Differentiation | Well | 33 | 32 | 1.00 | 0.567 | ||||
| Moderately | 7 | 12 | 1.77 | 0.62 | - | 5.06 | 0.288 | ||
| Poorly | 2 | 2 | 1.03 | 0.14 | - | 7.77 | 0.976 | ||
| Tumor site | Tongue | 26 | 26 | 1.00 | 0.544 | ||||
| Lower Gingiva | 5 | 11 | 2.20 | 0.67 | - | 7.22 | 0.194 | ||
| Upper Gingiva | 6 | 3 | 0.50 | 0.11 | - | 2.22 | 0.361 | ||
| Mouth floor | 3 | 4 | 1.33 | 0.27 | - | 6.56 | 0.723 | ||
| Buccal mucosa | 2 | 2 | 1.00 | 0.13 | - | 7.64 | 1.000 | ||
| Nuclear area | (µm2) | 73.4±19.4 | 97.8±29.9 | 1.04 | 1.02 | - | 1.07 | <0.001 | <0.001 |
| ≤80.3 | 33 | 15 | 1.00 | <0.001 | |||||
| >80.3 | 9 | 31 | 7.58 | 2.90 | - | 19.80 | <0.001 | ||
| Nuclear perimeter | (µm2) | 32.3±4.8 | 37.6±5.6 | 1.23 | 1.11 | - | 1.36 | <0.001 | <0.001 |
| ≤32.7 | 26 | 8 | 1.00 | <0.001 | |||||
| >32.7 | 16 | 38 | 7.72 | 2.88 | - | 20.70 | <0.001 | ||
| Circular rate | 0.82±0.05 | 0.80±0.04 | 0.44 | 0.18 | - | 1.09 | 0.075 | 0.075 | |
| Aspect ratio | 1.43±0.13 | 1.45±0.12 | 3.11 | 0.11 | - | 90.30 | 0.509 | 0.509 | |
| NACV | 31.5±6.6 | 33.9±6.4 | 1.06 | 0.99 | - | 1.13 | 0.095 | 0.095 | |
NACV: nuclear area coefficient of variation.