Table 2. Top 20 hits from univariate analyses examining genome-wide genetic variations related to placental abruption risk.

NCBIGene Name	SCANGene Name	SNP	MinorAllele	MAF	OR (95% CI)	Empiricalp-value
		rs544201	T	0.13	0.33 (0.21–0.54)	1.11E-05
CTNNA2	CTNNA2	rs1484464	G	0.3	1.80 (1.37–2.38)	2.62E-05
TNFRSF1A	TNFRSF1A	rs4149570	A	0.21	1.88 (1.40–2.53)	3.46E-05
ZNRF3	ZNRF3	rs13055470	A	0.31	0.52 (0.39–0.71)	3.54E-05
ACSL1	LOC11394	rs9997745	A	0.03	3.78 (1.97–7.26)	6.73E-05
		rs10754855	A	0.26	0.52 (0.38–0.72)	8.34E-05
		rs3096425	G	0.47	0.58 (0.44–0.76)	8.50E-05
		rs12896434	A	0.19	1.84 (1.36–2.49)	8.61E-05
		rs2436893	A	0.3	1.72 (1.31–2.25)	8.86E-05
LIPA	LIPA	rs7922269	A	0.44	0.58 (0.43–0.76)	1.03E-04
SCNN1A	SCNN1A	rs2228576	A	0.19	1.83 (1.34–2.48)	1.20E-04
ZBTB40	ZBTB4	rs12725956	G	0.08	2.24 (1.49–3.38)	1.20E-04
		rs3133572	A	0.15	0.44 (0.29–0.67)	1.28E-04
ZBED3-AS1		rs4457053	G	0.45	0.59 (0.46–0.78)	1.31E-04
ZBED3-AS1		rs7708285	G	0.45	0.59 (0.46–0.78)	1.36E-04
SDK2		rs9913193	G	0.25	0.54 (0.39–0.74)	1.38E-04
ADAMTS3	ADAMTS3	rs4694121	A	0.55	0.60 (0.46–0.78)	1.45E-04
		rs6871240	A	0.18	1.8 (1.33–2.46)	1.62E-04
PIEZO2		rs9964303	A	0.3	0.57 (0.42–0.76)	1.70E-04
		chr5∶76460816	C	0.45	0.60 (0.46–0.78)	0.000174

Abbreviations: MAF = Minor Allele Frequency in Controls.