Table 4. Top 20 SNPs in univariate analyses of candidate genes in relation to risk of placental abruption.

SCAN Gene Name	SNP	MinorAllele	MAF	OR (95% CI)	Empirical p-value
COX10	rs16949118	A	0.09	1.74 (1.17–2.59)	0.006003
THRB	rs7609948	A	0.19	1.48 (1.11–1.99)	0.008191
COX5A	chr15∶73015771	G	0.01	2.80 (1.09–7.21)	0.03232
THRB	rs17787283	A	0.12	0.64 (0.42–0.97)	0.03637
PRKCA	rs3848426	A	0.29	1.33 (1.02–1.74)	0.03651
PPARG	chr3∶12388339	C	0.23	1.37 (1.015–1.848)	0.03935
NDUFS4	rs1388111	A	0.51	0.78 (0.61–1.01)	0.05589
CAMK2B	chr7∶44224020	A	0.33	1.31 (0.99–1.72)	0.05679
CAMK2D	rs4834348	A	0.18	0.70 (0.49–1.01)	0.05689
PPARG	rs11709077	A	0.26	1.31 (0.98–1.75)	0.06663
NDUFC2-KCTD14	rs627297	C	0.18	0.74 (0.53–1.03)	0.07345
CAMK2B	chr7∶44224468	A	0.33	1.28 (0.97–1.69)	0.07898
THRB	rs12639293	A	0.29	1.28 (0.97–1.69)	0.07978
PPARG	chr3∶12326521	C	0.26	1.29 (0.96–1.72)	0.08784
PPARG	rs4135275	G	0.28	0.78 (0.58–1.05)	0.0958
NDUFS4	rs2168662	G	0.45	0.80 (0.62–1.04)	0.09672
TUFM	chr16∶28763228	A	0.24	0.76 (0.55–1.06)	0.1012
PPARG	chr3∶12344401	A	0.26	1.27 (0.95–1.69)	0.1048
PPARG	chr3∶12352344	A	0.3	0.79 (0.59–1.05)	0.1053
PPARG	chr3∶12340308	A	0.26	1.27 (0.95–1.69)	0.1059

Abbreviations: MAF = Minor Allele Frequency in Controls.