Table 5. Multiple logistic regression using SNPs selected in lasso regression.
Gene | SNP | SNPs in high LD* | Minor Allele | MAF | Odds Ratio | Empirical P-value | rank in univariate GWAS |
rs544201 | T | 0,13 | 0.33 (0.26–0.56) | 4,19E-05 | 1 | ||
CTNNA2 | rs1484464 | G | 0,30 | 1.69 (1.46–2.26) | 4,24E-04 | 2 | |
TNFRSF1A | rs4149570 | rs2228576 | A | 0,21 | 1.77 (1.53–2.41) | 2,58E-04 | 3 |
rs10754855 | A | 0,26 | 0.58 (0.49–0.81) | 1,35E-03 | 6 | ||
ARHGAP26 | rs17287593 | G | 0,01 | 4.55 (2.99–10.67) | 5,04E-04 | 47 | |
IFT46 | rs2277292 | rs2277295; rs17122278 | A | 0,05 | 0.23 (0.14–0.6) | 2,55E-03 | 60 |
*R2>0.8 within 500 kb.