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. 2014 Dec 30;9(12):e116346. doi: 10.1371/journal.pone.0116346

Table 7. Association between risk of placental abruption and weighted genetic risk score (WGRS) computed from SNPs selected in multivariable analyses using repeated 10-fold cross-validations.

Weighted Genetic Risk Score (GRS)
1st Quartile 2nd Quartile 3rd Quartile 4th Quartile p-value
Genome-wide Association Analysis*
OR ** 1 2.53 3.78 8.40 <0.001
(95% CI) (Ref.) (1.47–4.71) (2.2–6.4) (5.8–12.56)

*Cross-validated WGRS computed from SNPs selected from multivariable analyses.

**Cross-validated odds ratios (and 95% confidence intervals) from logistic regression models adjusted for sex, and population admixture, p-values associated to chi-square global test.