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. Author manuscript; available in PMC: 2014 Dec 30.
Published in final edited form as: Am J Hematol. 2009 Apr;84(4):221–227. doi: 10.1002/ajh.21363

Figure 4.

Figure 4

NO donor abolishes complement-mediated platelet activation. (A) Normalization of sP-selectin levels in mCd59ab+/+/C3+/+ or mCd59ab−/−/C3+/+ by injection of NOC-18 (0.02 mg/g body weight) (left panel) and SNAP (10 μg/g) (right panel) 15 min before L-NAME injection. (B) NO donor DEA/NO abolished the increased platelet consumption in mCd59ab−/−/C3+/+ mice. *: percent of 1 min platelet consumption in mCd59ab−/−/C3+/+ vs. in mCd59ab+/+/C3+/+, P < 0.01. All other pair-wise comparisons vs. mCd59ab+/+/C3+/+ were not statistically significant.