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. Author manuscript; available in PMC: 2016 Jan 15.
Published in final edited form as: Virology. 2014 Dec 8;475:204–218. doi: 10.1016/j.virol.2014.11.020

Fig. 12.

Fig. 12

A model for vaccinia virus structure. A) Last steps of morphogenesis starting with immature virion (IV), followed by the incorporation of a DNA molecule to form the immature virions with nucleoid (IVN) and the proteolysis of specific proteins to form the mature virion (MV). B) Fine detail of a sagittal section (see inset, lower left) of the MV showing the different virion sub-domains as specified on the left side of the figure. C) Same as B but the virions were treated with NP-40 and the virion lose the lipid content. D) Same as B but the virions were treated with NP-40+DTT and the virus lose the lipids and the membrane proteins.