Fig. 2.
4EBP1A4 effectively delays AKT/Ras induced hepatocarcinogenesis. (A) Gross images of livers, (B) survival curve, (C) liver weight and liver to body weight ratio of AKT/Ras/4EBP1WT (4EWT) and AKT/Ras/4EBP1A4 (4EA4) injected mice at different time points. Data are presented as mean ± SEM. ***P<0.001; ****P<0.0001. (D) HE image, HA-AKT, V5-4EBP1A4 staining in AKT/Ras/4EBP1A4 injected mouse liver 7 weeks post injection (W.P.I.). Magnifications: 100×; 400× (insets). 160×197mm (300 × 300 DPI)
