Table 1.
L-SED | O-SED | O-MOD EX | O-VIG EX | |
---|---|---|---|---|
Final body weight (g) | 467.33± 17.27a | 696.88± 12.38b | 580.75± 14.70c | 610.00± 10.66c |
DEXA body composition (% fat) | 14.5± 0.8a | 36.8± 1.4b | 24.1± 1.8c | 29.7± 1.1d |
Fat pad mass (g) | 14.65± 1.27a | 70.94± 4.20b | 40.30± 4.45c | 51.20± 3.57d |
Average weekly food intake (g/wk) | 149.18± 3.79a | 220.06± 3.32b | 202.19± 2.51c | 200.23± 5.00c |
Average relative weekly food weight (g food/g BW/wk) | 0.323± 0.003 | 0.339± 0.007 | 0.331± 0.007 | 0.319± 0.006 |
Heart weight : body weight | 3.11± 0.09a | 2.73±0.07b | 3.26± 0.07a | 3.20±0.07a |
Triglyceride (mg/dl) | 44.0± 3.7a | 343.4± 47.3b | 103.0± 9.8a,c | 114.0± 10.9c |
Free fatty acids (mmol/L) | 0.28± 0.02a | 0.89± 0.07b | 0.52± 0.04c | 0.61± 0.04c |
Leptin (pg/ml) | 18,144± 4,720a | 106,027± 10,531b | 39,285± 6,998a,c | 42,912± 6,784c |
MCP-1 (pg/ml) | 19.74± 10.47a | 49.04± 6.98b | 14.98± 6.49a | 26.92± 10.76a,b |
TNFα (pg/ml) | 3.16± 1.28 | 6.71± 3.10 | 4.55± 1.90 | 3.50± 1.21 |
IL-1β (pg/ml) | 0.84± 0 | 3.19± 1.73 | 5.71± 2.83 | 3.77± 1.58 |
IL-6 (pg/ml) | 3.41± 0.0a | 735.00± 182.14b | 227.43± 51.80a,c | 542.63± 84.91b,c |
IL-10 (pg/ml) | 30.43± 7.94a | 426.25± 86.03a,b | 1,001.73± 236.61c | 598.00± 149.48b,c |
Values are mean ±SE; n=8-10 animals per group. L-SED, LETO-sedentary; O-SED, OLETF-SED; MOD EX, moderate intensity exercise training; VIG EX, vigorous intensity interval training; MCP-1, monocyte chemoattractant protein; TNFα, tumor necrosis factor α; IL, interleukin. Fat pad mass was determined by summing the weights of the omental, retroperitoneal, and epididymal fat pads. Values with different letter superscripts are significantly different (p<0.05).