Table 3.

Course of patient no. 5. This patient has been suffering from WAIHA since 1992, and her hemolysis could not be compensated by standard therapy (table 2), but following treatment with ES As. Prior to the latter treatment, she was receiving low-dose prednisolone and cyclophosphamide since 2005

Date	Current therapy, mg/day		ESA, IU	Hb, g/dl	Retis, χ103/μ1	LDH, U/l	DAT
	Pred	Cyclo					IgG	C3d
March 15, 2012	7.5	100	–	7.9	77	373	4+	3+
March 22, 2012 to May 4, 2012	7.5	100	3×40,000 U/w	n.t.	n.t.	n.t.	n.t.	n.t.
April 26, 2012	7.5	–	–	9.8	84	290	3+	3+
June 14, 2012	7.5	–		9.9	108	288	4+	3+
June 18, 2012 to June 25, 2012	7.5	–	3× 40,000 U/w	n.t.	n.t.	n.t.	n.t.	n.t.
December, 7, 2012	7.5	–	–	10.8	99		4+	3+
October 25, 2012 to December 12, 2012	10	–	3× 40,000 U	10.5	99	277	n.t.	n.t.
January 24, 2013	7.5	–	–	13.2	54	254	3+	3+
March 5, 2013	7.5	–	40,000	11.9
March 14, 2012	7.5	–	–	12.3
April 30, 2013	5	–	–	12.3	40	254	3+	1+
September 2, 2013	5		40,000	10.6	33		2+	2+
September 18, 2013	5		40,000	11.8	49	252	1+	1+

Pred = Prednisolone; Cyclo = cyclophosphamide; Hb = hemoglobin; Retis = reticulocytes; LDH = lactate dehydrogenase; DAT = direct antiglobulin test.