Fig. 2.

Blood from transgenic HOD.FVB or HOD.B6 animals was leukoreduced and stored for 28–35 days. A, B The equivalent of 1 human ‘unit’ was transfused into C57BL/6 mice, with recipient anti-HOD Ig immune responses measured by flow cytometric cross-match 14 days post-transfusion. C, D Post-transfusion RBC survival and recovery studies were completed, using monoclonal antibodies against Fy3 to track the transfused HOD RBCs.