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Oral administration of pure HCT and optimized SNEDDS formulation F2 compared to control and placebo in Wistar rats.
| Treatment | HCT | SNEDDS | Control | Placebo |
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| Period 1 | Group 1 | Group 2 | Group 3 | Group 4 |
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| Washout period of 72 hours | ||||
| Period 2 | Group 2 | Group 3 | Group 4 | Group 1 |
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| Washout period of 72 hours | ||||
| Period 3 | Group 3 | Group 4 | Group 1 | Group 2 |
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| Washout period of 72 hours | ||||
| Period 4 | Group 4 | Group 1 | Group 2 | Group 3 |
