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. 2014 Dec 18;6(12):3471–3487. doi: 10.3390/toxins6123471

Figure 3.

Figure 3

The phylogenetic tree constructed for the secretory PLA2s of snakes and mammals, based on the amino acid sequences of their mature proteins. The numerals at the nodes represent bootstrap confidence values and the branch lengths represent the numbers of amino acid substitutions per site. Abbreviations: Bt, Bos taurus; Cf, Canis lupus familiaris; Gg, Gallus gallus; Mc, Macaca mulatta; Oa, Ornithorhynchus anatinus; Oc, Oryctolagus cuniculus; and Pn, Pan troglodytes. References: BtIIEPLA2 (NP_001179015) [33], CfIIEPLA2 (XP_544525) (automated computational prediction by GNOMON); DtDis-2 (AFH66959) [17]; GgIBPLA2 (NP_001138961) [34]; GgIIEPLA2 (NP_001171878) [35]; HsIBPLA2 (NP_000919) [36]; HsIIAPLA2 (NP_001155199) [37]; HsIICPLA2 (NP_001099042) [38]; HsIIDPLA2 (NP_036532) [39]; HsIIFPLA2 (NP_073730) [40]; HsVPLA2 (NP_000920) [38]; LmLei-2 (AFH66961) [17]; LmLei-3 (AFH66962) [17]; McIIEPLA2 (XP_001094364) (automated computational prediction by GNOMON); MmIBPLA2 (NP_035237) [41]; MmIIAPLA2 (NP_001076000) [42]; MmIICPLA2 (NP_032894) [41]; MmIIDPLA2 (NP_035239) [39]; MmIIFPLA2 (NP_036175) [20]; MmVPLA2 (NP_001116426) [41]; OaIIEPLA2 (XP_001505559) (automated computational prediction by GNOMON); OcIIEPLA2 (XP_002716050) (automated computational prediction by GNOMON); OoIIEPLA2 (this work); PeIIEPLA2 (this work); PfIIEPLA2 (this work); PnIIEPLA2 (XP_001163677) (automated computational prediction by GNOMON); and PtIIEPLA2 (this work).