Skip to main content
. 2014 Dec 8;111(51):18249–18254. doi: 10.1073/pnas.1415120112

Table 2.

Pathways with the largest location or expression changes

Tissue L:P E:P L:A E:A Pathway
Breast + HTLV I infection
+ One carbon pool by folate
+ Proteasome
+ ErbB signaling
Liver + Axon guidance
+ GPI anchor biosynthesis
+ Hypertrophic cardiomyopathy
+ Dilated cardiomyopathy
Prostate + Fatty acid elongation
+ HIF-1 signaling
+ Oxidative phosphorylation
+ PPAR signaling
+ Viral myocarditis
Bladder + + Hippo signaling
+ NF-κB signaling
+ p53 signaling
+ Transcription misregulation in cancer
+ Apoptosis
+ Cell cycle
+ mRNA surveillance
+ Ribosome biogenesis

Pathway P values were calculated by using individual protein location (L) or expression (E) P values from the pipeline (L:P, E:P) and using P values from pathologist annotations (L:A, E:A). Plus symbol indicates pathway P < 0.01. Values for all pathways are in Dataset S3.