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Comparison of optogenetic evoked pulse-like increments in LH secretion and endogenous LH pulses. (A) Dynamics of continuous 10-Hz 2- and 5-min evoked LH increments by stimulating the cell bodies (gray, black lines) or the distal projections (yellow, blue lines) of GnRH neurons compared with endogenous LH pulses (red) overlaid upon one another. Mean + SEM values are shown. (B) Dynamics of evoked and endogenous LH pulses after normalizing values to the peak LH responses for each response.
