Table 2.

Statistical results of GO classification in ME pretreatment group.

Term	Count	Up	Upregulated	Down	Downregulated
Cell adhesion	11	3	Pcdhb9, Igfals, Pcdh9	8	Ptprm, Dsg2, Pdpn, Trpm7, Icam2, Lmo7, Postn, Spp1
Peptidase activity	12	4	Acr, Eml2, Cndp1, Xpnpep3	8	Mmp10, Bace2, Serpine1, Serpinb2, Fgl2, Apaf1, Mysm1, Mmp12
Regulation of angiogenesis	4	1	Figf	3	Col4a2, Ptprm, Serpine1
Cytokine activity	5	1	Il33	4	Il23a, Ccl2, Ccl27, Spp1
Ion binding	36	14	Cndp1, Pcdhb9, Trim50, Cacnb2, Necab2, Vwde, Scd, Tmem38b, Ng35, Cyp17a1, Pcdh9, Arsg, Xpnpep3, Cyp4f1	22	Syt4, Lmo7, Plcb4, Pak3, Acsl4, Zc3h14, Micall2, Trpm7, Csrp3, March11, Mmp12, Tmem38b, Mmp10, Plekhf2, Baz1a, Trim33, Dsg2, Prdm6, Hivep2, Zfp281, Slc5a7, Prkd3
Multicellular organism reproduction	9	4	Acr, Avpr1a, Micalcl, Pcdhga11	5	Ccl2, Ccnd2, Acsl4, Vgf, Prl8a2
Others	31	9	Matn3, Igfals, Il33, Metrn, Figf, Avpr1a, Slc30a8, Scd, Penk	22	Col4A2, Ccl2, Loc363458, Postn, Vgf, Mmp12, Mmp10, L23a, Adm, Wasl, Serpinb2, Sema3c, Spp1, Ccl27, Serpine1, Prl8a2, Ptprm, Pdpn, Trpm7, Gas7, Col4a3bp, Serpin
Total	108	36		72

Note. Upregulated means upregulated genes, Downregulated means downregulated genes.