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Number of micronuclei (MN) in ERK1/2 inhibitor-treated Colo320DM cells
|
MN-DM+ |
MN-DM− |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Colo320DM cells | No. of cells | No. of cells with MNs | MN frequency (×10−2) | No. of MN- DM+ | MN-DM+ /MN (%) | Frequency (×10−2) | Fold change over control | Frequency (×10−2) | Fold change over control |
| DMSO | 1499 | 38 | 2.54 | 20 | 52.63 | 1.33 | 1.00 | 1.20 | 1.00 |
| U0126 | 1769 | 94 | 5.31 | 49 | 52.13 | 2.77 | 2.08 | 2.54 | 2.12 |
| PD98059 | 1552 | 91 | 5.86 | 52 | 57.14 | 3.35 | 2.51 | 2.51 | 2.09 |
