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. 2014 Dec 31;12:771. doi: 10.1186/s12915-014-0099-8

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© Madon-Simon et al.; licensee BioMed Central. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Whole body, liver wet weight and relative liver weight analysis of one-week-old mice. A) Significantly increased body weights were noted in Grb10 ^m/+ compared to wild type and Dlk1 ^+/p and in Grb10 ^m/+ /Dlk1 ^+/p compared to Dlk1 ^+/p mice whereas weights of Dlk1 ^+/p animals did not differ from wild types. B) Analysis of wet weights of the livers revealed significant enlargement in Grb10 ^m/+ compared to wild type and Dlk1 ^+/p mice and in Grb10 ^m/+ /Dlk1 ^+/p compared to Dlk1 ^+/p animals. C) No differences were found in relative liver weights. D) Table summarising results of statistical analysis. All values represent means ± SEM, analysed using one way ANOVA with Tukey’s post-hoc analysis. WT n = 10, Dlk1 ^+/p n = 9, Grb10 ^m/+ n = 15, Grb10 ^m/+ /Dlk1 ^+/p n = 8; * P <0.05; *** P <0.001. ANOVA, analysis of variance; SEM, standard error of the mean; WT, wild type.