Table 1.
Subject characteristics
| GOLD stage | N | Age (yrs) | Male/Female | Pack years | FEV1 % predicted | FEV1/FVC % | DLCO % predicted | Diagnoses |
|---|---|---|---|---|---|---|---|---|
| Non-smokers | 4 | 59 ± 8 | 2/2 | O | 90 ± 5 | 82 ± 3 | 71 ± 4 | 4 Carcinoid |
| Control Smokers | 18 | 67 ± 8 | 11/7 | 38 ± 19 | 98 ± 13 | 76 ± 4 | 80 ± 15 | 6 Squamous |
| 7 Adeno | ||||||||
| 4 Large cell | ||||||||
| 1 Small cell | ||||||||
| 1 | 9 | 61 ± 11 | 6/3 | 50 ± 14 | 89 ± 6 | 66 ± 4 | 78 ± 21 | 4 Squamous |
| 3 Adeno | ||||||||
| 1 Large cell | ||||||||
| 1 Small cell | ||||||||
| 2 | 9 | 63 ± 9 | 6/3 | 50 ± 21 | 66 ± 7 | 58 ± 4 | 68 ± 17 | 1 Squamous |
| 5 Adeno | ||||||||
| 1 Large cell | ||||||||
| 1 Poorly differentiated | ||||||||
| 1 Amyloid | ||||||||
| 3 | 3 | 67 ± 5 | 2/1 | 49 ± 12 | 46 ± 1 | 53 ± 9 | 56 ± 14 | 1 Adeno (BAC) |
| 1 Squamous | ||||||||
| 1 Carcinoid |
Means ± SD. An ANOVA showed no significant difference in age by GOLD category but significant differences for pack years, FEV1 % predicted, FEV1/FVC % and DLCO % Predicted. (p < 0.0001 for all comparisons) Among smokers there was no significant difference in pack years by GOLD category. Control smokers – 14/21 Current smokers, GOLD 1 - 6/9 Current smokers. GOLD 2 – 9/10 Current smokers and GOLD 3 – 2 Current smokers and one status unknown. Current smoker = within 6 months of surgical resection.