TABLE 1.
BASELINE VALUES
| VARIABLE | ALL PATIENTS (N =100) | FEMALES (N =39) | MALES (N =61) | P value |
|---|---|---|---|---|
|
| ||||
| Age, yrs. | 53 ± 1 | 53 ± 1 | 53 ± 1 | n.s. |
| Body weight, lb | 192 ± 3 | 168 ± 5 | 207 ± 3 | 0.001 |
| Body Mass Index, Kg x m2 | 28.62 ± 0.39 | 27.96 ± 0.78 | 29.04 ± 0.39 | n.s. |
| Systolic Blood Pressure, mm Hg | 147 ± 1 | 148 ± 1 | 146 ± 2 | n.s. |
| Diastolic Blood Pressure, mm Hg | 93 ± 1 | 91 ± 1 | 94 ± 1 | n.s. |
| Heart Rate, beats x min−1 | 74 ± 1 | 75 ± 1 | 73 ± 1 | n.s. |
| Fasting Blood glucose, mg x dL−1 | 97.19 ± 0.89 | 96.05 ± 1.36 | 97.92 ± 1.18 | n.s. |
| Serum Creatinine, mg x dL−1 | 0.87 ± 0.02 | 0.75 ± 0.03 | 0.92 ± 0.02 | 0.001 |
| Plasma Glucose, mg x dL−1 | 97.19 ± 0.89 | 96.05 ± 1.36 | 97.92 ± 1.17 | n.s. |
| Plasma Insulin, μU x mL−1 | 8.46 ± 0.97 | 7.57 ± 1.71 | 9.02 ± 1.17 | n.s. |
| Plasma Leptin, μg x L−1 | 12.64 ± 1.01 | 20.11 ± 1.88 | 7.87 ± 0.53 | 0.001 |
| Plasma Angiotensin II, fmol x mL−1 | 42.35 ± 1.65 | 48.96 ± 2.95 | 38.13 ± 1.74 | 0.001 |
| Plasma Angiotensin-(1-7), fmol x mL−1 | 13.08 ± 2.10 | 11.47 ± 1.16 | 14.10 ± 3.36 | n.s. |
| Serum Aldosterone, ng x dL−1 | 11.29 ± 0.56 | 13.17 ± 1.07 | 10.08 ± 0.56 | 0.006 |
| Hs-C Reactive Protein, mg x dL−1 | 0.30 ± 0.03 | 0.45 ± 0.06 | 0.21 ± 0.03 | 0.0005 |
| Serum ICAM, ng x dL−1 | 200 ± 6 | 199 ± 8 | 200 ± 9 | n.s. |
| Serum VCAM, ng x dL−1 | 569 ± 19 | 550 ± 28 | 580 ± 25 | n.s. |
| Serum P-selectin, ng x dL−1 | 100 ± 3 | 101 ± 4 | 100 ± 4 | n.s. |
| Serum TGF-β, ng x mL−1 | 17.08 ± 0.61 | 18.40 ± 0.87 | 16.25 ± 0.82 | n.s. |
| Serum TNF-α, pg x mL−1 | 25.32 ± 1.50 | 24.26 ± 2.57 | 25.98 ± 1.84 | n.s. |
Values are means ± SEM of variables obtained at week -1. P value within Table denotes statistical differences between female and males.