Skip to main content
. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Biomarkers. 2014 Mar 6;19(3):222–230. doi: 10.3109/1354750X.2014.897757

Figure 2.

Figure 2

Dose-response of plasma ASS and ALT in APAP-treated mice. Mice were treated with PBS vehicle, 100, or 150 mg/kg acetaminophen (APAP) and sacrificed 6 h later. (A) Plasma alanine aminotransferase (ALT). (B) Plasma argininosuccinate synthetase (ASS). (C) H&E stained liver sections from the 100 and 150 mg/kg APAP-treated mice. Data are expressed as mean ± SEM for n = 3-4. *p < 0.05 compared with PBS vehicle.