Table III.
Comparison of renal oxidative stress parameters following contrast media injection (mean±standard deviation; n=8).
| Group | MDA (nmmol/mg protein) | SOD (U/mg protein) | NADPH oxidase (U/mg protein) |
|---|---|---|---|
| NN | 3.43±0.47 | 413.03±23.28 | 14.95±5.12 |
| HN | 4.21±0.75 | 394.67±43.62 | 21.26±8.26a |
| HL | 8.46±0.92a,b | 317.01±47.36a,b | 82.42±31.18a,b |
| HLP | 5.27±0.48c | 422.32±41.50c | 26.59±7.56c |
a
P<0.01, versus the NN group;
b
P<0.01, versus the HN group;
c
P<0.01, versus the HL group.
NN, normal diet group; HN, high cholesterol diet group; HL, high cholesterol plus low-osmolar contrast media iohexol group; HLP, high cholesterol plus iohexol plus pentoxifylline group; NADPH oxidase, nicotinamide adenine dinucleotide phosphate-oxidase; MDA, malondialdehyde; SOD, superoxide dismutase.