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Significant association between HMGB1 expression levels and overall survival rates of patients. A significantly negative correlation was identified between the intensity of HMGB1 expression and survival rate. There appeared to be a stronger correlation with reduced survival times for patients with HGG than for patients with LGG (P=0.045). LGG, low-grade glioma; HGG, high-grade glioma; HMGB1, high-mobility group box-1.
