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. Author manuscript; available in PMC: 2015 Jan 25.
Published in final edited form as: Science. 2014 Jul 25;345(6195):455–459. doi: 10.1126/science.1249749

Fig. 1. Progressive neurodegeneration in the nmf205−/− mice.

Fig. 1

(A to F) Hematoxylin and eosin (H and E) stained sagittal sections of nmf205−/− and wild-type (WT; +/+) cerebella. (E and F) Higher-magnification images of cerebellar lobule IX from (C and D). (G and H) Cerebellar sections were immunostained with antibodies to cleaved caspase-3 (c-Casp3; green) and counterstained with Hoechst 33342. (I to L) H and E-stained sagittal sections of the dentate gyrus (I and J) and retina (K and L). Scale bars, 1 mm (D), 50 µm (F and J), and 100 µm (H and L). ONL, outer nuclear layer; OPL, outer plexiform layer; INL, inner nuclear layer; IPL, inner plexiform layer; GCL, ganglion cell layer.