Table 1. Summary of phenotypes.
developmental | progressive | ||||||||||
eclosion | longevity | geotaxis | spontaneous activity | ||||||||
total activity | peak ratio | ||||||||||
Htt | ATXN1 | Htt | ATXN1 | Htt | ATXN1 | Htt | ATXN1 | Htt | ATXN1 | ||
pan-neuronal | elav | − | + | ± | − | − | − | − | − | − | − |
1407 | − | +++ | ± | + | − | − | − | − | + | + | |
motor neuron | OK6 | − | + | ++ | ++ | + | + | − | − | − | − |
D42 | + | + | ++ | + | − | + | − | − | − | − | |
cholinergic | cha | +++ | − | +++ | − | ++ | ± | − | − | + | + |
dopaminergic | ple | +++ | lethal | ++ | ++ | − | + | ||||
glia | repo | − | lethal* | +++ | +++ | − | −** |
− not significant in comparison with three controls (UAS, GAL4 and short Q).
± significant but slight (<20%) difference.
+ less than 2 fold difference.
++ more than 2 fold difference.
+++ more than 3 fold difference.
* severe toxicity in short Q control.
** shift of peak time in short Q control.