Table 2. Summary of the relationship between expression level and phenotype.
expression level | phenotype | |||
developmental | progressive | |||
elav | Htt | + | − | + |
ATXN1 | + | + | − | |
1407 | Htt | ++ | − | ± |
ATXN1 | +++ | +++ | + | |
OK6 | Htt | ++ | − | ++ |
ATXN1 | ++ | + | ++ | |
D42 | Htt | ++ | + | ++ |
ATXN1 | ++ | + | + | |
cha | Htt | ++ | +++ | +++ |
ATXN1 | ++ | − | + | |
ple | Htt | +++ | +++ | ++ |
ATXN1 | lethal | lethal | lethal |
expression level:
+; 2000–2500 copies/µg total RNA.
++; 4000–6500 copies/µg total RNA.
+++; 8000– copies/µg total RNA.
phenotype:
development = eclosion.
progressive = The strongest of progressive phenotypes (longevity, geotaxis or spontaneous activity).
These data are employed from table 1.
− not significant.
± significant but slight (<20%) difference.
+ less than 2 fold difference.
++ more than 2 fold difference.
+++ more than 3 fold difference.