Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Reagents and conditions: (a) (CH2O)n (5.43 equiv), AcOH, 75 °C; (b) DMSO (27 equiv), (COCl)2 (14 equiv), Et3N (5.2 equiv), CH2Cl2, −78 °C to rt; (c) NH2OH·HCl, pyr (9.3 equiv), MeOH, 65 °C; (d) TsCl (1.1 equiv), DIPEA (2.6 equiv), CH2Cl2.
