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. 2014 Dec 31;9(12):e115613. doi: 10.1371/journal.pone.0115613

Table 3. Survival in Patients with Appendiceal Carcinoma by the Log-Rank Test (n = 108).

No.patients 5-year survival rate P Value
Category (%) (%)
Age (yrs) 0.054
<65 47 (43.5) 72.4
≥65 61 (56.5) 53.6
Gender 0.296
Men 55 (50.9) 57.4
Women 53 (49.1) 65.9
Histological typea
pap, well, mod 68 (63) 67.7 0.226
por, sig 19 (17.6) 48.8
muc 21 (19.4) 60.3
Tumor depthb 0.066
m, sm, mp 26 (24.1) 84
ss, se, si 82 (75.9) 57.6
Lymph node metastasisc 0.04
Negative 55 (67.9) 76.1
Positive 26 (32.1) 47.7
Lymphatic invasion 0.02
Negative 56 (51.9) 77.6
Positive 52 (48.1) 47
Venous invasion <0.001
Negative 75 (69.4) 73.7
Positive 33 (30.6) 35.4
Curabilityd <0.001
Curative resection 64 (61) 83
Non-curative resection 41 (39) 28.5
MUC1 0.626
Negative 57 (52.8) 63.1
Positive 51 (47.2) 62
MUC2 0.072
Negative 31 (28.7) 51.3
Positive 77 (71.3) 66.5
MUC3 0.004
Negative 88 (81.5) 69.1
Positive 20 (18.5) 38.8
MUC4 0.467
Negative 7 (6.5) 47.6
Positive 101 (93.5) 63.4
MUC5AC 0.433
Negative 54 (50) 59.1
Positive 54 (50) 66.1
MUC6 0.698
Negative 103 (95.4) 61.6
Positive 5 (4.6) 75
MUC16 0.061
Negative 90 (83.3) 65.4
Positive 18 (16.7) 48.1
MUC17 0.5
Negative 15 (13.9) 67.5
Positive 93 (86.1) 61.9
a

pap, papillary adenocarcinoma; well, well differentiated adenocarcinoma; mod, moderately differentiated adenocarcinoma; por, poorly differentiated adenocarcinoma; sig, signet-ring cell carcinoma; muc, mucinous carcinoma.

b

m, mucosa; sm, submucosa; mp, muscularis propria; ss, subserosa, se, serosa; si, invasion to other organ.

c

27 cases without lymph node dissection were excluded.

d

3 cases with unknown details regarding curative or non-curative resection were excluded.