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. 2014 Dec 31;9(12):e115835. doi: 10.1371/journal.pone.0115835

Table 2. High frequency regions (HFRs) of focal aberrations and gene(s) within or overlapping these HFRs.

HFR1 Focal abberration Focal2 Total3
Chrom. Start (bp) End (bp) Size (kb) Gain Loss Gain Loss Genes
1 68394382 68461186 67 2 0 10 0 GPR177
1 166259174 166263398 4 2 0 8 0 IQWD1
1 145961855 146262362 301 2 1 8 1 FAM108A2, NBPF11
2 51022554 51022614 0.06 2 0 3 1 NRXN1
2 153790092 154905667 1116 2 0 3 1 RPRM, GALNT13
2 212844992 212863839 19 1 3 1 5 ERBB4
2 237017756 237067914 50 0 3 1 8 IQCA1
3 38177003 38246945 70 1 2 1 6 OXSR1
3 57426028 57504090 78 0 2 0 8 DNAH12L
3 59855182 59891414 36 0 2 0 9 FHIT
3 60208127 60420353 212 0 2 0 9 FHIT
3 24260772 24290280 30 0 3 0 5 THRB
3 32341229 32364439 23 0 3 0 6 CMTM8
4 90072621 90081252 9 0 2 1 3 FAM13A1
4 183476755 184028352 552 0 2 1 7 ODZ3
4 73484965 73485361 0.396 0 15 0 17 ADAMTS3
5 170214294 170645196 431 1 2 1 5 RANBP17
5 55470977 55502030 31 0 2 1 10 ANKRD55
5 110611609 110683366 72 0 2 0 8 CAMK4
5 135294758 135330960 36 0 2 0 8 FBXL21, LECT2
5 158336707 158375568 39 0 4 0 7 EBF1
5 58765648 58766102 0.454 0 5 0 12 PDE4D
5 80023854 80024518 0.664 0 11 0 14 MSH3
6 44998738 45119343 121 5 0 11 0 SUPT3H
6 13965760 14255124 289 2 1 4 1 CD83, RNF182
6 14051934 14103151 51 2 1 4 1 RNF182
6 86262042 86335470 73 0 3 0 11 SNX14, NT5E
6 110510873 110539046 28 0 4 0 12 WASF1
7 57480106 57659360 179 2 0 3 1 ZNF716
7 63149422 63486197 337 2 0 3 1 ZNF679, ZNF735
7 943615 954205 11 1 2 1 3 ADAP1
7 15536047 15536441 0.394 0 6 0 7 TMEM195
8 128437695 130578879 2141 4 1 14 1 TMEM75, MYC, POU5F1P1
8 124855221 124894704 39 3 0 17 0 FAM91A1
8 132030642 132421393 391 2 0 16 0 ADCY8
8 64257961 64390486 133 2 1 12 1 YTHDF3
8 145064850 145118710 54 2 1 11 1 PLEC1
8 25130171 25130291 0.12 1 14 1 15 DOCK5
9 3339487 3417226 78 1 2 1 8 RFX3
9 71289871 71308842 19 0 2 0 5 APBA1
9 87357661 87432833 75 0 3 0 5 AGTPBP1
9 33230225 33242111 12 0 8 0 12 SPINK4
10 115580402 115675237 95 1 2 1 11 NHLRC2, DCLRE1A
10 25604754 25659341 55 1 3 1 15 GPR158
10 15898437 15929438 31 0 2 0 16 C10orf97
10 38082301 38147982 66 0 2 1 11 ZNF248
10 71648150 71656573 8 0 2 0 12 PPA1
10 123566469 123752493 186 0 2 1 13 TACC2, NSMCE4A, ATE1
10 89716166 89756083 40 0 3 0 14 PTEN
10 72166137 72172267 6 0 4 0 12 ADAMTS14
11 20922810 20971401 49 0 2 0 3 NELL1
11 92517181 92571937 55 0 2 0 5 SLC36A4
11 104441220 104484303 43 0 2 0 4 CARD17
11 47391562 47453463 62 0 3 0 3 CUGBP1, RAPSN, PSMC3, SLC39A13
11 102486510 102663548 177 0 4 0 5 DYNC2H1
12 51710169 51719305 9 0 2 0 5 EIF4B
12 91645948 91679726 34 0 2 1 5 PLEKHG7
12 18413696 18414167 0.471 0 4 1 7 PIK3C2G
13 92502207 93946439 1444 1 2 1 12 DCT, GPC6
13 34399863 34517051 117 0 5 0 14 NBEA
14 59138607 59161895 23 2 1 5 1 RTN1
14 69961223 69998909 38 0 6 0 6 ADAM21, ADAM21P
15 59943982 60046989 103 0 2 1 3 VPS13C
16 87557619 87557679 0.06 1 2 1 8 CBFA2T3
16 87527215 87549395 22 1 3 1 9 CBFA2T3
16 71734726 71798103 63 0 2 0 6 C16orf47
16 45728834 45887805 159 0 4 0 6 ITFG1, NETO2
17 37018570 37057586 39 0 4 1 7 KRT42P, KRT17, KRT16
19 33996261 34984966 989 4 1 12 1 C19orf12, PLEKHF1, POP4, VSTM2B, UQCRFS1, UQCRFSL1
19 532070 556653 25 0 4 1 4 HCN2, BSG
19 60711906 60737394 25 0 4 1 6 SBK2
X 33147645 33243866 96 1 6 1 15 DMD
1

HFR: common region of focal aberration (gain or loss);

2

Focal: number of samples with focal aberration;

3

Total: total number of samples containing the HFR of the focal aberration. Genes in bold have been reported in the Cancer Gene Census list.