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. 2014 Dec 31;9(12):e116125. doi: 10.1371/journal.pone.0116125

Table 1. The highly kidney-enriched genes according to the transcriptome profiling.

Gene name Description Main localisation Kidney mRNA TS score HPA
UMOD Uromodulin Membrane 1421 647 Yes
SLC22A8 Solute carrier family 22, member 8 Membrane 269 633 Yes
SLC12A1 Solute carrier family 12, member 1 Membrane 406 460 Yes
TMEM174 Transmembrane protein 174 Membrane 97 443 Yes
MCCD1 Mitochondrial coiled-coil domain 1 Membrane 27 271 Yes
SLC34A1 Solute carrier family 34, member 1 Membrane 176 219 Yes
AQP2 Aquaporin 2 (collecting duct) Membrane 315 177 Yes
SLC22A12 Solute carrier family 22, member 12 Membrane 108 162 Yes
SLC22A2 Solute carrier family 22, member 2 Membrane 97 154 Yes
SLC22A6 Solute carrier family 22, member 6 Membrane 198 144 No
KCNJ1 Potassium inwardly-rectifying channel Membrane 132 140 Yes
SLC7A13 Solute carrier family 7, membrane 13 Membrane 19 118 No
NPHS2 Nephrosis 2, idiopathic, (podocin) Membrane 68 116 Yes
SLC6A18 Solute carrier family 6, member 18 Membrane 11 106 Yes
SLC36A2 Solute carrier family 36, member 2 Membrane 64 97 Yes
SLC12A3 Solute carrier family 12, member 3 Membrane 129 84 Yes
SLC22A13 Solute carrier family 22, member 13 Membrane 12 74 Yes
ATP6V1G3 ATPase, H+ transporting, lysosomal Membrane 38 73 Yes
MIOX Myo-inositol oxygenase Cytoplasm 625 73 Yes
TMEM207 Transmembrane protein 207 Membrane 10 59 Yes

‘Kidney mRNA’ shows the average FPKM value in the kidney samples, ‘TS’ shows the tissue specificity score and ‘HPA’ shows if there was corresponding data in the Human Protein Atlas. Individual FPKM values and variance in the four different kidney samples are found in S3 File.