Table 1. Demographic data of the Dutch and Spanish cohort.

	Dutch cohort			Spanish cohort
	Cases	Controls		Cases	Controls
	=  Ototoxicity	=  No ototoxicity		=  Ototoxicity	=  No ototoxicity
	N = 42	N = 68	p-value	N = 16	N = 22	p-value
Age at diagnosis (y)	15	15	0.82	11.5	14	0.23
median, range	(5–40)	(7–39.3)		(4–29)	(7–28)
Gender (male)	22	33	0.6	15	6	0.1
N, %	(40%)	(60%)		(71.4%)	(28.6%)
Cumulative dose cisplatin (mg/m2)	500	480	1	504	515	0.32
median, range	(100–600)	(200–600)		(120–870)	(140–720)
Concomitant drugs
Vincristine (N, %)	3 (2.7%)	2 (1.8%)	0.3	2 (5.2%)	4 (10.5%)	0.13
Aminoglyocide antibiotics (N, %)	0	0		15 (68.2%)	10 (62.5%)	0.74
Otoprotectants (N, %)	0	0		0	0