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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Trends Genet. 2014 Oct 2;31(1):34–40. doi: 10.1016/j.tig.2014.09.001

Figure 5.

Figure 5

HGIs can cause differences in the phenotypic variance of the two alleles at a locus. (A) Two parents that differ at three interacting loci are crossed. Only one of the eight haploid recombinant genotypes possesses the alleles required for the HGI (denoted with a red arrow). (B) Phenotypes of the eight possible haploid recombinants are plotted by their allele at locus 1. The individual carrying the interacting combination of alleles denoted with a red arrow and has a higher phenotypic value than the other genotypes. (C) Potential effect of the HGI on the phenotypic variance associated with the two alleles at locus 1. The orange allele shows an appreciably higher phenotypic variance than the blue allele due to some individuals possessing the interacting combination of alleles. The bars depict confidence intervals of an arbitrary level (e.g., 95%).