Table 3.
Multivariate COX regression analysis evaluating PRELP and RPS8 staining with PDAC survival.
| A. PRELP Bottom Tertile Staining in Multivariate Analysis | ||||
|---|---|---|---|---|
|
| ||||
| Variable | P value | HR | 95% CI Lower | 95%CI Upper |
|
| ||||
| High grade | 0.039 | 1.511 | 1.022 | 2.235 |
| pN1 | 0.012 | 1.632 | 1.116 | 2.388 |
| BottomTertile_PRELP | 0.062 | 0.684 | 0.459 | 1.019 |
| B. RPS8 Top Quartile Staining in Multivariate Analysis | ||||
|---|---|---|---|---|
|
| ||||
| Variable | P value | HR | 95% CI Lower | 95%CI Upper |
|
| ||||
| Female | 0.081 | 1.398 | 0.96 | 2.037 |
| High Grade | 0.003 | 1.788 | 1.217 | 2.627 |
| pN1 | 0.026 | 1.546 | 1.053 | 2.272 |
| TopQuartile_RPS8 | 0.012 | 1.806 | 1.139 | 2.863 |
| C. Combination of “LowRPS8 and HighPRELP” vs. all others | ||||
|---|---|---|---|---|
|
| ||||
| Variable | P value | HR | 95% CI Lower | 95%CI Upper |
|
| ||||
| Female | 0.074 | 1.407 | 0.967 | 2.049 |
| High grade | 0.035 | 1.521 | 1.03 | 2.247 |
| pN1 | 0.024 | 1.555 | 1.059 | 2.283 |
| LowRPS8_HighPRELP | 0.024 | 0.638 | 0.432 | 0.942 |
| D. Combination of “HighRPS8 and LowPRELP” vs. all others | ||||
|---|---|---|---|---|
|
| ||||
| Variable | P value | HR | 95% CI Lower | 95%CI Upper |
|
| ||||
| High grade | 0.008 | 1.686 | 1.146 | 2.481 |
| pN1 | 0.009 | 1.682 | 1.136 | 2.49 |
| HighRPS8_LowPRELP | 0.001 | 2.685 | 1.464 | 4.924 |