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Homology models of human IRS-1 and IRS-2 retrieved through I-TASSER. Five models were predicted as possible 3D structures for both IRS-1 and IRS-2 proteins. The best model for each protein was selected on the basis of Ramachandran plots and their geometrical configuration. (a) Human IRS-1 full-length predicted 3D structures by I-TASSER with Ramachandran plots and geometry. (b) Human IRS-2 predicted 3D structures by I-TASSER with Ramachandran plots and geometry.
