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Alignment of mammalian NPC2 sequences. The 19 amino acid signal sequences are shown. NPC2 sequences are numbered starting with the first amino acid after the signal peptide, marked with an arrow. Residues with hydrophobic side chains are colored in red, and residues with hydrophilic side chains are colored in blue (acidic), magenta (basic) and green (neutral). * indicates identical residues, : indicates conserved residues, and . indicates semi-conserved residues.
