TABLE 1.
Genes induced by Notch in C2C12 myoblasts.
| Affymetrix ID | Fold changea | Gene Symbol | Description | ||
|---|---|---|---|---|---|
| 1 | 1417985_at | 14.02 | [C] | Nrarp | Notch-regulated ankyrin repeat protein |
| 2 | 1419302_at | 10.86 | [C] | Heyl | hairy/enhancer-of-split related with YRPW motif-like |
| 3 | 1415999_at | 7.818 | [C] | Hey1 | hairy/enhancer-of-split related with YRPW motif 1 |
| 4 | 1450297_at | 6.389 | [C] | Il6 | interleukin 6 |
| 5 | 1418417_at | 5.204 | [C] | Msc | musculin [MyoR] |
| 6 | 1426640_s_at | 4.982 | [C] | Trib2 | expressed sequence AW319517 [Tribbles2] |
| 7 | 1433837_at | 4.743 | [C] | 8430408G22Rik | RIKEN cDNA 8430408G22 [G22] |
| 8 | 1439794_at | 4.483 | [C] | Ntn4 | netrin 4 |
| 9 | 1418937_at | 4.324 | [NT] | Dio2 | deiodinase, iodothyronine, type II |
| 10 | 1421106_at | 4.066 | [NT] | Jag1 | jagged 1 |
| 11 | 1436033_at | 3.979 | [C] | BC031353 | cDNA sequence BC031353 |
| 12 | 1420757_at | 3.328 | [C] | Myf5 | myogenic factor 5 |
| 13 | 1436570_at | 3.242 | [NT] | BG143461 | EST mab56d07.x1 |
| 14 | 1434140_at | 3.151 | [C] | Mcf2l | mcf.2 transforming sequence-like |
| 15 | 1424530_at | 3.122 | [C] | Sec14l2 | SEC14-like 2 (S. cerevisiae) |
| 16 | 1448886_at | 3.104 | [NC] | Gata3 | GATA binding protein 3 |
| 17 | 1434430_s_at | 3.093 | [NT] | Adora2b | adenosine A2b receptor |
| 18 | 1440990_at | 2.994 | [C] | 4832420M10 | hypothetical protein 4832420M10 |
| 19 | 1450922_a_at | 2.954 | [NC] | Tgfb2 | transforming growth factor, beta 2 |
| 20 | 1428250_at | 2.927 | [C] | Gpr30 | G protein-coupled receptor 30 |
| 21 | 1435888_at | 2.923 | [C] | Egfr | epidermal growth factor receptor |
| 22 | 1440761_at | 2.85 | [NT] | 4833422C13Rik | RIKEN cDNA 4833422C13 |
| 23 | 1417122_at | 2.71 | [C] | Vav3 | vav 3 oncogene |
| 24 | 1416613_at | 2.699 | [NT] | Cyp1b1 | cytochrome P450, family 1, subfamily b, polypeptide 1 |
| 25 | 1438531_at | 2.656 | [NT] | A730054J21Rik | RIKEN cDNA A730054J21 |
| 26 | 1454768_at | 2.618 | [NT] | Kcnf1 | potassium voltage-gated channel, subfamily F, member 1 |
| 27 | 1429021_at | 2.601 | [NT] | Epha4 | Eph receptor A4 |
| 28 | 1425814_a_at | 2.595 | [NT] | Calcrl | calcitonin receptor-like |
| 29 | 1416630_at | 2.579 | [C] | Id3 | inhibitor of DNA binding 3 |
| 30 | 1456830_at | 2.557 | [NT] | Ppp1r2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 |
a
Targets subsequently confirmed by RT-PCR are marked “C”, those not confirmed are marked “NC”, and those not tested are marked “NT”.