Table 1.
Rates of antipsychotic prescribing by class of antipsychotic, age gender and social deprivation
Any antipsychotic |
Any first-generation antipsychotic |
Any second-generation antipsychotic |
First-generation and second-generation antipsychotics |
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---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Rate per 100 000 PYAR | 95% CI | IRR* | 95% CI | Rate per 100 000 PYAR | 95% CI | IRR* | 95% CI | Rate per 100 000 PYAR | 95% CI | IRR* | 95% CI | Rate per 100 000 PYAR | 95% CI | IRR* | 95% CI | |
Male | 612 | (607 to 617) | 1.000 | 197 | (194 to 200) | 1.000 | 458 | (454 to 462) | 1.000 | 43 | (41 to 44) | 1.000 | ||||
Female | 699 | (693 to 705) | 1.092 | (1.088 to 1.095) | 256 | (253 to 259) | 1.204 | (1.196 to 1.211) | 489 | (484 to 493) | 1.050 | (1.046 to 1.054) | 46 | (44 to 47) | 1.010 | (1.096 to 1.103) |
Under 18 | 63 | (61 to 66) | 0.044 | (0.044 to 0.045) | 5 | (4 to 5) | 0.009 | (0.008 to 0.009) | 59 | (57 to 62) | 0.058 | (0.057 to 0.059) | 0.6 | (0.4 to 0.9) | 0.026 | (0.026 to 0.027) |
18–29 | 459 | (451 to 467) | 0.351 | (0.349 to 0.353) | 111 | (107 to 115) | 0.223 | (0.220 to 0.227) | 376 | (369 to 383) | 0.401 | (0.398 to 0.404) | 28 | (26 to 30) | 0.348 | (0.346 to 0.351) |
30–39 | 817 | (806 to 828) | 0.804 | (0.799 to 0.808) | 238 | (232 to 244) | 0.643 | (0.636 to 0.650) | 638 | (628 to 648) | 0.867 | (0.861 to 0.872) | 58 | (56 to 62) | 0.803 | (0.799 to 0.807) |
40–49 | 852 | (842 to 863) | 1.000 | 289 | (283 to 295) | 1.000 | 628 | (619 to 637) | 1.000 | 64 | (62 to 67) | 1.000 | ||||
50–59 | 712 | (701 to 723) | 0.872 | (0.867 to 0.877) | 283 | (276 to 290) | 1.045 | (1.035 to 1.056) | 483 | (474 to 492) | 0.804 | (0.799 to 0.809) | 54 | (51 to 57) | 0.872 | (0.867 to 0.877) |
60–69 | 642 | (631 to 653) | 0.824 | (0.819 to 0.829) | 281 | (274 to 289) | 1.039 | (1.029 to 1.050) | 406 | (398 to 415) | 0.740 | (0.735 to 0.745) | 46 | (43 to 49) | 0.824 | (0.819 to 0.829) |
70–79 | 842 | (827 to 857) | 0.973 | (0.967 to 0.980) | 350 | (341 to 360) | 1.192 | (1.179 to 1.205) | 546 | (534 to 559) | 0.888 | (0.881 to 0.894) | 54 | (51 to 58) | 0.971 | (0.965 to 0.977) |
80+ | 2201 | (2170 to 2231) | 2.234 | (2.222 to 2.246) | 793 | (775 to 811) | 2.358 | (2.334 to 2.382) | 1529 | (1504 to 1555) | 2.185 | (2.171 to 2.199) | 121 | (114 to 129) | 2.221 | (2.209 to 2.234) |
Townsend | ||||||||||||||||
Least deprived | 403 | (398 to 409) | 1.000 | 138 | (135 to 142) | 1.000 | 291 | (286 to 296) | 1.000 | 26 | (24 to 27) | 1.000 | ||||
2 | 499 | (492 to 506) | 1.211 | (1.203 to 1.218) | 180 | (176 to 184) | 1.251 | (1.237 to 1.265) | 351 | (345 to 357) | 1.194 | (1.186 to 1.203) | 33 | (31 to 35) | 1.214 | (1.207 to 1.222) |
3 | 645 | (637 to 653) | 1.707 | (1.697 to 1.716) | 223 | (218 to 228) | 1.764 | (1.745 to 1.782) | 465 | (458 to 472) | 1.683 | (1.672 to 1.695) | 43 | (41 to 45) | 1.714 | (1.705 to 1.724) |
4 | 844 | (834 to 854) | 2.457 | (2.443 to 2.470) | 295 | (290 to 301) | 2.516 | (2.491 to 2.542) | 608 | (600 to 616) | 2.432 | (2.416 to 2.448) | 59 | (57 to 62) | 2.476 | (2.463 to 2.489) |
Most deprived | 1158 | (1145 to 1172) | 3.587 | (3.567 to 3.606) | 386 | (378 to 394) | 3.649 | (3.612 to 3.686) | 853 | (841 to 865) | 3.560 | (3.537 to 3.583) | 80 | (76 to 84) | 3.613 | (3.593 to 3.633) |
Missing | 806 | (781 to 830) | 2.282 | (2.259 to 2.305) | 270 | (256 to 284) | 2.360 | (2.315 to 2.406) | 586 | (566 to 608) | 2.250 | (2.223 to 2.277) | 51 | (45 to 57) | 2.187 | (2.165 to 2.210) |
Year | ||||||||||||||||
2007 | 591 | (584 to 599) | 1.000 | 236 | (231 to 241) | 1.000 | 399 | (393 to 405) | 1.000 | 44 | (42 to 46) | 1.000 | ||||
2008 | 654 | (646 to 663) | 1.075 | (1.069 to 1.080) | 243 | (238 to 248) | 0.990 | (0.981 to 1.000) | 456 | (449 to 463) | 1.118 | (1.111 to 1.125) | 45 | (43 to 47) | 1.075 | (1.070 to 1.081) |
2009 | 679 | (670 to 687) | 1.110 | (1.104 to 1.115) | 237 | (232 to 242) | 0.946 | (0.938 to 0.955) | 487 | (480 to 494) | 1.194 | (1.186 to 1.201) | 45 | (43 to 47) | 1.108 | (1.102 to 1.114) |
2010 | 718 | (710 to 727) | 1.151 | (1.145 to 1.157) | 227 | (222 to 232) | 0.880 | (0.872 to 0.888) | 536 | (529 to 543) | 1.290 | (1.282 to 1.298) | 44 | (42 to 47) | 1.147 | (1.141 to 1.153) |
2011 | 637 | (629 to 646) | 1.065 | (1.059 to 1.071) | 189 | (184 to 193) | 0.745 | (0.737 to 0.752) | 492 | (484 to 499) | 1.230 | (1.222 to 1.238) | 43 | (41 to 45) | 1.055 | (1.050 to 1.061) |
*All IRR are adjusted for the other characteristics in this table.
IRR, incident rate ratio; PYAR, person years at risk.