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. 2014 Dec 31;4(12):e005664. doi: 10.1136/bmjopen-2014-005664

TableĀ 4 .

Performance characteristics of RPR tests for diagnosis of syphilis

Non-treponemal tests TPPA
Positive Negative
HBI HiSens Auto RPR Positive 31 3
Negative 28 50
Sensitivity 52.5% (95% CI 39.1% to 65.7%)
Specificity 94.3% (95% CI 84.3% to 98.8%)
Positive predictive value 91.2% (95% CI 76.3% to 98%)
Negative predictive value 64.1% (95% CI 52.4% to 74.7%)
TPPA
Positive Negative
BD Macro-Vue RPR card Positive 51 3
Negative 8 50
Sensitivity 86.4% (95% CI 75% to 93.9%)
Specificity 94.3% (95% CI 84.3% to 98.8%)
Positive predictive value 94.4% (95% CI 84.6% to 98.8%)
Negative predictive value 86.2% (95% CI 74.6% to 93.8%)

RPR, rapid plasma reagin; TPPA, Treponema pallidum particle agglutination.