Table I.
The number of IGHV genes and allelic variants identified in VDJ gene rearrangements from 12 individuals
| Mean No. per Individual ± SEM |
Range | |
|---|---|---|
| Functional IGHV genesa | 43.1 ± 0.5 | 40–46 |
| Pseudogenesa | 6.8 ± 0.3 | 4–8 |
| Homozygous genes | 40.2 ± 0.8 | 34–43 |
| Heterozygous genes (two alleles) | 8.6 ± 0.9 | 3–13 |
| Heterozygous genes (three alleles) | 1.1 ± 0.3 | 0–3 |
| Unreported polymorphisms | 1.8 ± 0.5 | 0–5 |
a
Genes were classified as functional genes or as pseudogenes by reference to the IMGT information system (17).