Table 2.

Metabolites with altered levels in Oat1-deficient mice

Metabolite	Phenotype	Reference Nos.
2-Hydroxy-3-methylvalerate	Elevated plasma concentration	74
2-Hydroxyisovalerate	Reduced urine concentration	74
2-Oxo-3-methylvalerate	Reduced urine concentration	74
2-Oxoisocaproate	Reduced urine concentration	74
3-Hydroxypropionate	Elevated plasma concentration	74
3-Hydroxyvalerate	Reduced urine concentration	74
3-Hydroxybutyrate	Elevated plasma concentration	74
3-Hydroxyisobutyrate	Elevated plasma concentration	74
3-Methylcrotonylglycine	Reduced urine concentration	74
4-Hydroxyphenylacetate	Reduced urine concentration	74
4-Hydroxyphenyllactate	Elevated plasma conc./reduced urine conc.	74
4-Hydroxyphenylpyruvate	Reduced urine concentration	74
4-Pyridoxic acid	Elevated plasma concentration	279
5-Methyl cytidine	Reduced urine concentration	279
Amino-cresol sulfate	Reduced urine concentration	279
Benzoate	Elevated plasma concentration	74
Creatinine	Reduced renal secretion	264
Hexanoylglycine	Reduced urine concentration	74
Indole lactic acid	Elevated plasma concentration	279
Indoxyl sulfate	Elevated plasma concentration	279
Kynurenine	Elevated plasma concentration	279
Mercurials	Protective from mercurial renal toxicity	249
Methionine	Elevated plasma concentration	279
N2-N2-dimethyl guanosine	Reduced urine concentration	279
N-acetylaspartate	Elevated plasma conc./reduced urine conc.	74
N-acetylglycine	Reduced urine concentration	279
N-methyl adenosine	Reduced urine concentration	279
Orotate	Reduced urine concentration	74
Orotic acid	Reduced urine concentration	279
Pantothenic acid	Elevated plasma concentration	279
Phenyl sulfate	Elevated plasma concentration	279
Phenylacetyl glycine	Elevated plasma concentration	279
p-Hydroxy phenyllactic acid	Elevated plasma concentration	279
Propionylglycine	Reduced urine concentration	74
Thymidine	Reduced urine concentration	279
Uracil	Reduced urine concentration	74
Urate	Decreased secretion/reduced urine conc.	73, 279
Xanthurenic acid	Reduced urine concentration	279
α-Ketoglutarate	Reduced plasma conc./elevated urine conc.	74