Fig. 5.

Identification and quantification of metabolites negatively correlated with SM and significantly decreased by d-flow. Of 22 ions shown in Table 2, 8 most significant and functionally known metabolites are quantified comparing between s-flow and d-flow (A–H). The metabolites include sphingosine [M+H, m/z 300.2897 (A), sphingosine M+H-H₂O, m/z 282.2791 (B)], sphinganine (m/z 302.3053) (C), LysoPE (m/z 528.3059) (D), phosphatidylcholine (PC; m/z 562.3492) (E), phosphatidylglycerol (PG; m/z 773.4734) (F), PC (m/z 784.5862) (G), LysoPE (m/z 524.2764) (H), lactosylceramide (m/z 996.7294) (I), and phosphatidylinositol (PI; m/z 631.3133) (J). *P < 0.05. Detailed information of these ions was provided in Table 2.