FIGURE 2.
Cartilage-specific deletion of Hdac7 decreases bone accrual. A and B, representative three-dimensional reconstructions of trabecular bone from the distal femur of Hdac7Col2ERT mice treated with vehicle or tamoxifen. C, bone volume per total tissue volume (BV/TV), D, trabecular thickness (Tb. Th.), E, trabecular number (Tb. N.), and F, trabecular spacing (Tb. Sp.) from the distal femur are also shown (n = 5 per group). G, cortical bone density was measure at the femoral diaphysis. *, p < 0.05 compared with control.