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Summary of the characterization of 66 GαS mutants
GTPγS binding and in vitro activation of adenylyl cyclase (AC) were shown as percentage of the values obtained with wild-type GαS. The increase of cAMP in cells is shown as the fold increase from each individual experiment. ΔN31 and ΔN38 are deletion mutants of the N-terminal 31 or 38 amino acids, respectively.
